BDBM10885 (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide::(R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-E)-1,2-thiazine-6-sulfonamide 1,1-dioxide::AL-4862::Azopt::Brinzolamide (BRZ)::brinzolamide
SMILES CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
InChI Key InChIKey=HCRKCZRJWPKOAR-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 41 hits for monomerid = 10885
Affinity DataKi: 3nMAssay Description:Compound was evaluated for binding affinity against human carbonic anhydrase II (hCA -II)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II) by esterase methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme I by esterase assay method.More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibitory activity against Human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
Affinity DataKi: 15nM ΔG°: -10.7kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of human cloned CA1 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 730nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 6 hrs prior to testing measured for 10 to 100 secs by phenol red-based stopped-flo...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase I by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 1 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant CA1More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant cytosolic isozyme CA I by stopped-flow CO2 hydrase methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase-1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant Carbonic anhydrase 1 compound preincubated for 15 mins by stopped flow CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human carbonic anhydrase-1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of full length human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of full length human CA 1More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human CA1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human carbonic anhydrase-1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measure...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human full length carbonic anhydrase 1 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair